Vibrio cholerae Response Regulator VxrB Controls Colonization and Regulates the Type VI Secretion System.
Published in PLoS pathogens
Two-component signal transduction systems (TCS) are used by bacteria to sense and respond to their environment. TCS are typically composed of a sensor histidine kinase (HK) and a response regulator (RR). The Vibrio cholerae genome encodes 52 RR, but the role of these RRs in V. cholerae pathogenesis is largely unknown. To identify RRs that control V...