Telisinghe, L Waite, T D Gobin, M Ronveaux, O Fernandez, K Stuart, J M Scholten, R J P M
Published in
Epidemiology and infection
Household contacts of an index case of invasive meningococcal disease (IMD) are at increased risk of acquiring disease. In revising WHO guidance on IMD in sub-Saharan Africa, a systematic review was undertaken to assess the effect of chemoprophylaxis and of vaccination in preventing subsequent cases of IMD in household contacts following an index c...
Hellenbrand, W Hanquet, G Heuberger, S Nielsen, S Stefanoff, P Stuart, J M
Published in
Epidemiology and infection
We performed a systematic literature review to assess the effectiveness of chemoprophylaxis for contacts of sporadic cases of invasive meningococcal disease (IMD) in educational settings. No studies directly compared IMD risk in contacts with/without chemoprophylaxis. However, compared to the background incidence, an elevated IMD risk was identifie...
Hoek, M R Christensen, H Hellenbrand, W Stefanoff, P Howitz, M Stuart, J M
Published in
Epidemiology and infection
SUMMARYWe performed a systematic review to estimate the effectiveness of vaccination, in addition to chemoprophylaxis, in preventing meningococcal disease among household contacts. Medline, EMBASE, EMGM, and EUIBIS were used for data collection. Studies reporting on at least 100 primary cases and on subsequent cases in household settings with follo...
